An Acetyltransferase Conferring Tolerance to Toxic Aromatic Amine Chemicals

An acetyltransferase conferring tolerance to toxic aromatic amine chemicals: molecular and functional studies.

Aromatic amines (AA) are a major class of environmental pollutants that have been shown to have genotoxic and cytotoxic potentials toward most living organisms. Fungi are able to tolerate a diverse range of chemical compounds including certain AA and have long been used as models to understand general biological processes. Deciphering the mechanisms underlying this tolerance may improve our und...

Pesticides and toxic chemicals

‘Contamination’ is a comparative term. In Britain at least, contaminants are trace substances; in the context of food they are distinguished from additives by whether or not there is an intention that the substances should be present when the food is consumed or prepared for consumption. Contaminants may be of natural or of technological origin: and technological contaminants may be direct or i...

ToxiC inhalaTional injury and ToxiC indusTrial ChemiCals

Pesticides and toxic chemicals.

‘Contamination’ is a comparative term. In Britain at least, contaminants are trace substances; in the context of food they are distinguished from additives by whether or not there is an intention that the substances should be present when the food is consumed or prepared for consumption. Contaminants may be of natural or of technological origin: and technological contaminants may be direct or i...

Toxic nephropathy: environmental chemicals.

The kidney is the target of numerous xenobiotic toxicants, including environmental chemicals. Anatomical, physiological, and biochemical features of the kidney make it particularly sensitive to many environmental compounds. Factors contributing to the sensitivity of the kidney include: large blood flow, the presence of a variety of xenobiotic transporters and metabolizing enzymes, and concentra...